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Multiple Choice

Congenital toxoplasmosis can cause which combination of outcomes?

Congenital toxoplasmosis from a fetal infection often damages the central nervous system and eyes. The brain involvement can cause hydrocephalus from disruption of CSF dynamics and inflammatory injury, and it frequently leads to neurodevelopmental issues such as cognitive deficits. Hearing loss can accompany this CNS damage, and chorioretinitis (eye involvement) is a common accompanying feature, though not required to be listed here. This combination—hydrocephalus with hearing loss and cognitive impairment—best reflects the CNS and sensory sequelae produced by congenital toxoplasmosis. Other options lack this characteristic CNS/eye-pattern or point to different congenital infections, making them less typical for toxoplasmosis.

Congenital toxoplasmosis from a fetal infection often damages the central nervous system and eyes. The brain involvement can cause hydrocephalus from disruption of CSF dynamics and inflammatory injury, and it frequently leads to neurodevelopmental issues such as cognitive deficits. Hearing loss can accompany this CNS damage, and chorioretinitis (eye involvement) is a common accompanying feature, though not required to be listed here. This combination—hydrocephalus with hearing loss and cognitive impairment—best reflects the CNS and sensory sequelae produced by congenital toxoplasmosis. Other options lack this characteristic CNS/eye-pattern or point to different congenital infections, making them less typical for toxoplasmosis.