Toxoplasmosis can be associated with which neurologic or ocular manifestations?

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Toxoplasma gondii infection can involve the nervous system and eyes across different scenarios. It can cause neurologic problems such as encephalitis with seizures, focal deficits, and altered mental status, and it can affect the eyes with retinitis or chorioretinitis that may leave scars. In congenital infection, key outcomes include hydrocephalus, cognitive deficits, and hearing loss, with potential long-term neurodevelopmental impact. Some studies have also noted associations between latent toxoplasmosis and certain neuropsychiatric conditions like bipolar disorder and schizophrenia.

The best choice reflects this full spectrum: neurologic issues plus ocular involvement and congenital sequelae, which together capture the range of neurologic and ocular manifestations associated with toxoplasmosis. Other options mention features that are not characteristic or are far less specific to toxoplasmosis, such as a skin rash and fever, gastrointestinal symptoms only, or isolated muscle weakness.