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Multiple Choice

What is the described route of transmission for Borna virus?

No confirmed natural transmission route for Borna virus has been established in humans. While Borna disease virus is known to cause disease in animals and can be studied experimentally, epidemiologic and clinical data do not definitively prove a specific route of spread among people. That uncertainty is why the best answer is unknown—the evidence does not support a consistent direct contact, inhalation, or vector-borne transmission pathway in humans. In other words, although exposure to infected animals or their secretions is suspected in some cases, there is no proven, universal transmission route, so labeling it unknown best reflects current knowledge.

No confirmed natural transmission route for Borna virus has been established in humans. While Borna disease virus is known to cause disease in animals and can be studied experimentally, epidemiologic and clinical data do not definitively prove a specific route of spread among people. That uncertainty is why the best answer is unknown—the evidence does not support a consistent direct contact, inhalation, or vector-borne transmission pathway in humans. In other words, although exposure to infected animals or their secretions is suspected in some cases, there is no proven, universal transmission route, so labeling it unknown best reflects current knowledge.