Which tissues are known to harbor FMD virus when preserved for testing?

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Multiple Choice

Which tissues are known to harbor FMD virus when preserved for testing?

FMDV can be shed and persist in tissues beyond the surface lesions, so certain tissues are more reliable for detecting the virus in preserved samples. Lymph nodes and bone marrow are rich sites where viral RNA or infectious virus can be found because of viral escape into the immune and reticuloendothelial systems during infection. Visceral organs (the viscera) also harbor the virus during systemic involvement, making them good sources for diagnostic testing when samples are preserved for later analysis. Brain and spinal cord are not typical reservoirs for FMDV in diagnostic testing, and hair or nails do not harbor the virus. Blood and urine may contain viral material transiently, but they are less reliable as preserved-tissue sources for routine testing compared with lymphoid and visceral tissues.

FMDV can be shed and persist in tissues beyond the surface lesions, so certain tissues are more reliable for detecting the virus in preserved samples. Lymph nodes and bone marrow are rich sites where viral RNA or infectious virus can be found because of viral escape into the immune and reticuloendothelial systems during infection. Visceral organs (the viscera) also harbor the virus during systemic involvement, making them good sources for diagnostic testing when samples are preserved for later analysis.

Brain and spinal cord are not typical reservoirs for FMDV in diagnostic testing, and hair or nails do not harbor the virus. Blood and urine may contain viral material transiently, but they are less reliable as preserved-tissue sources for routine testing compared with lymphoid and visceral tissues.

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